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Karthik Clinic & Karthik Ultrasound Scan Centre
MICO Layout, II Stage, Arekere, Bannerghatta Road, Bangalore - 560076
Fetal Medicine

Maternal Serum Screening Test

All women, whatever their age, have a small risk of delivering a baby with physical and/or mental disability. In some cases the disability is due to chromosomal abnormalities such as in Downs Syndrome. Downs Syndrome is a chromosomal disorder caused by the presence of an extra chromosome 21 (trisomy 21) in the cells of the developing fetus which can manifest in children with varying degrees of mental disabilities, congenital heart diseases, gastrointestinal abnormalities, poor muscle tone etc. This is known to occur in 1 in every 600 pregnancies around the world. About 50% of the fetuses with Downs syndrome abort and 50% of them will survive to delivery.

As the maternal age increases the relative risk of having a baby with Downs syndrome increases, the risk doubles at maternal age of 35 years. Hence screening tests should be offered to all pregnant women.

Screening test can be done in the First or Second trimester

First trimester screening test (FTS) or the Combined test which is done between 11-14 weeks is unique as it involves a combination of ultrasound (nuchal translucency) and a maternal blood test to identify biochemical markers (Beta HCG and PAPP A – double markers) in conjunction with maternal age. This helps in picking up 90% (I.e. 9 out of 10 cases) of Downs syndrome.


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Services offered:
  • Early Pregnancy Scan
  • 11-14 Weeks (NT) Scan
  • Mid Trimester Anomaly Scan with Doppler
  • Interval Growth Scan with Doppler
  • End Term Assessment Scan with Doppler
  • 3D/4D Scan
  • Pelvic Scan
  • Abdomino Pelvic Scan
  • Breast Scan
  • Neonatal Abdoment Scan
Aneuploidy Screening
  • First Trimester Screening Test (FTS)
  • Second Trimester Screening Test
  • (Quadruple & Triple)
Genetic Counseling Consultations
  • General
  • Antenatal
  • Paediatric
  • Well-Woman Check Up including PAP Smear
  •   Ultrasound
  •   Aneuploidy Screening
  •   Genetic Counseling Consultations

Ultrasound training
  • To gain knowledge of the basics of ultrasound physics
  • To be confident in performing a targeted obstetric scan and identify the common fetal anomalies
  • Understanding fetal biometry
  • To image the normal uterus and adnexae and identify their pathology

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